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When compared with usual care, nurses instituted pharmacologic therapy for lipid management more often ().

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Metoprolol Dilated Cardiomyopathy (MDC) trial had assessed the effects of metoprolol tartrate on the combined endpoint of mortality and heart transplantation with similar results ().

Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs.

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Impaired renal function is associated with echocardiographic nonresponse and poor prognosis after cardiac resynchronization therapy.

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In conclusion, in patients at least 65 years of age, with mildly to moderately symptomatic CHF and impaired LVEF, initiation of treatment for CHF with bisoprolol followed by combined therapy with enalapril, as compared with the opposite order, showed similar rates of combined death and all-cause hospitalization and a trend toward improved survival.

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Bisoprolol inhibits renin secretion by about 65% and tachycardia by about 30%.

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The heart rate change over time recorded 2 months after randomization was significantly linked with baseline heart rate in both study treatment groups.

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