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Metoprolol Dilated Cardiomyopathy (MDC) trial had assessed the effects of metoprolol tartrate on the combined endpoint of mortality and heart transplantation with similar results ().

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Impaired renal function is associated with echocardiographic nonresponse and poor prognosis after cardiac resynchronization therapy.

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Bisoprolol inhibits renin secretion by about 65% and tachycardia by about 30%.

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